RFC-1 Gene Expression Regulates Folate Absorption in Mouse Small Intestine
نویسندگان
چکیده
منابع مشابه
Effect of arsenic on neural tube in mouse embryo and relation to reduced folate carrier (RFC-1)
Arsenic is an important environmental toxicant which is usually found in drinking water in inorganic form. The hypothesis tested in this investigation is; arsenic exposure causes neural tube defects (NTDs) andthese defects of the central nervous system are more likely related to folate deficiency during fetal life. In this study, sodium arsenate was administered via intraperitoneal route at a r...
متن کاملAlcohol and absorption from the small intestine. 1. Impairment of absorption from the small intestine in alcoholics.
An absorption screen was performed in 10 chronic alcoholic patients within a few days of admission due to an acute alcoholic episode. Impaired absorption of d-Xylose was noted in three patients and low leucocyte ascorbic acid and serum folate levels in five. No abnormality was detected in jejunal histology. The absorption of water and electrolytes from the jejunum was studied in these patients ...
متن کاملKrüppel-like factor 4 regulates adaptive expression of the zinc transporter Zip4 in mouse small intestine.
Epithelial cells of the small intestine are the site of zinc absorption. Intestinal uptake of zinc is inversely proportional to the dietary supply of this essential micronutrient. The mechanism responsible for this adaptive differential in apical zinc transport is not known. The zinc transporter Zip4 (Slc39a4) is essential for adequate enteric zinc uptake. In mice, Zip4 expression is upregulate...
متن کاملeffect of arsenic on neural tube in mouse embryo and relation to reduced folate carrier (rfc-1)
arsenic is an important environmental toxicant which is usually found in drinking water in inorganic form. the hypothesis tested in this investigation is; arsenic exposure causes neural tube defects (ntds) andthese defects of the central nervous system are more likely related to folate deficiency during fetal life. in this study, sodium arsenate was administered via intraperitoneal route at a r...
متن کاملAlcohol and absorption from the small intestine
Absorption of electrolytes from the intestinal lumen into the blood stream involves, predominantly, the process of active transport. Energy for cellular metabolism derives from the splitting of the high energy phosphate bond of adenosine triphosphate (ATP) by the enzyme adenosine triphosphatase (ATPase), (Brooks, 1973). Ethanol has been shown to affect the ATP content in several tissues and it ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1997
ISSN: 0021-9258
DOI: 10.1074/jbc.272.17.11165